Like a winding stream, the River Heritage Region of Southeast Missouri reveals beauty, wonder, and inspiration at every turn. Delicately preserved river towns & quaint country villages and towns charm guests with turn-of-the-century architecture, antique shops, and historic sites. Our region is the agricultural garden of Missouri, rich in cultural history, intriguing attractions, fun-filled festivals and spectacular scenery.

This region brings charm and the unexpected to every aspect of your Missouri Vacation. Come discover Southeast Missouri.

2017 Christmas Midnight Mass at the National Shrine
Kids Count Down to New Year
La Guignolee Watch Party
Bootheel Youth Museum Mardi Gras 2018 Benefit Dinner & Auction
Oran 4th of July Picnic
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The Glenn House

325 S. Spanish St.
Cape Girardeau County

East Prairie Chamber of Commerce

106 S. Washington St.
Mississippi County

Tour de Corn Bike Ride

219 N Washington St.
Mississippi County


River Heritage Association
437 Main Street :: New Madrid, MO 63869
573-748-2684 ::

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